শুক্রবার, ৩০ নভেম্বর, ২০১২

Oceanic crust breakthrough: Solving a magma mystery

Oceanic crust breakthrough: Solving a magma mystery [ Back to EurekAlert! ] Public release date: 29-Nov-2012
[ | E-mail | Share Share ]

Contact: Frances Jenner
fjenner@ciw.edu
202-478-8459
Carnegie Institution

Washington, D.C. Oceanic crust covers two-thirds of the Earth's solid surface, but scientists still don't entirely understand the process by which it is made. Analysis of more than 600 samples of oceanic crust by a team including Carnegie's Frances Jenner reveals a systemic pattern that alters long-held beliefs about how this process works, explaining a crucial step in understanding Earth's geological deep processes. Their work is published in Nature on November 29.

Magmas generated by melting of the Earth's mantle rise up below the oceanic crust and erupt on the Earth's surface at mid-ocean ridge systems, the longest mountain ranges in the world. When the magma cools it forms basalt, the planet's most-common rock and the basis for oceanic crust.

It has long been assumed that the composition of magmas erupting out of mid-ocean ridges is altered when minerals that form during cooling sink out of the remaining liquid, a process called fractional crystallization. In theory, trace elements that are not included in the crystallizing minerals should be little affected by this process, and their ratios should be the same in the erupting magma as they were in the original magma before cooling.

If this is true, trace element ratios in magmas erupting at mid-ocean ridges should represent those of the original parental magma that formed deep in the Earth's mantle. However, this process doesn't account for the high abundance of trace elements found in samples of basalt from mid-ocean ridges around the world, so the reality of the situation is obviously more complicated than previous theories indicated.

Using the extensive array of samples and advanced modeling, Jenner and her research partner Hugh O'Neill of the Australian National University demonstrated that the concentration of trace elements is due to the process by which the magma is cycled through the oceanic crust prior to being erupted on the sea floor at the mid-ocean ridges.

Magma collects under the Earth's surface in a pool of liquid rock called a magma chamber. Each chamber is frequently flushed with new magma, which mixes with the old magma that was already there, and then this blended magma erupts out onto the ocean floor. Following the influx of new magma and eruption, the remaining magma undergoes fractional crystallization. This means that minerals are separated out from the magma as it cools. However, these minerals contain only minor amounts of the trace elements. As a result, trace elements build up in the magma over time, as the magma chamber is continually replenished by new magma coming in to the system.

"It's a simple idea, but it fits remarkably well," Jenner said. "These new findings will permit us to explore the conditions of mantle melting and production of the Earth's most-common rock."

###

This work was funded by the Australian National University.

The Carnegie Institution for Science is a private, nonprofit organization headquartered in Washington, D.C., with six research departments throughout the U.S. Since its founding in 1902, the Carnegie Institution has been a pioneering force in basic scientific research. Carnegie scientists are leaders in plant biology, developmental biology, astronomy, materials science, global ecology, and Earth and planetary science.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Oceanic crust breakthrough: Solving a magma mystery [ Back to EurekAlert! ] Public release date: 29-Nov-2012
[ | E-mail | Share Share ]

Contact: Frances Jenner
fjenner@ciw.edu
202-478-8459
Carnegie Institution

Washington, D.C. Oceanic crust covers two-thirds of the Earth's solid surface, but scientists still don't entirely understand the process by which it is made. Analysis of more than 600 samples of oceanic crust by a team including Carnegie's Frances Jenner reveals a systemic pattern that alters long-held beliefs about how this process works, explaining a crucial step in understanding Earth's geological deep processes. Their work is published in Nature on November 29.

Magmas generated by melting of the Earth's mantle rise up below the oceanic crust and erupt on the Earth's surface at mid-ocean ridge systems, the longest mountain ranges in the world. When the magma cools it forms basalt, the planet's most-common rock and the basis for oceanic crust.

It has long been assumed that the composition of magmas erupting out of mid-ocean ridges is altered when minerals that form during cooling sink out of the remaining liquid, a process called fractional crystallization. In theory, trace elements that are not included in the crystallizing minerals should be little affected by this process, and their ratios should be the same in the erupting magma as they were in the original magma before cooling.

If this is true, trace element ratios in magmas erupting at mid-ocean ridges should represent those of the original parental magma that formed deep in the Earth's mantle. However, this process doesn't account for the high abundance of trace elements found in samples of basalt from mid-ocean ridges around the world, so the reality of the situation is obviously more complicated than previous theories indicated.

Using the extensive array of samples and advanced modeling, Jenner and her research partner Hugh O'Neill of the Australian National University demonstrated that the concentration of trace elements is due to the process by which the magma is cycled through the oceanic crust prior to being erupted on the sea floor at the mid-ocean ridges.

Magma collects under the Earth's surface in a pool of liquid rock called a magma chamber. Each chamber is frequently flushed with new magma, which mixes with the old magma that was already there, and then this blended magma erupts out onto the ocean floor. Following the influx of new magma and eruption, the remaining magma undergoes fractional crystallization. This means that minerals are separated out from the magma as it cools. However, these minerals contain only minor amounts of the trace elements. As a result, trace elements build up in the magma over time, as the magma chamber is continually replenished by new magma coming in to the system.

"It's a simple idea, but it fits remarkably well," Jenner said. "These new findings will permit us to explore the conditions of mantle melting and production of the Earth's most-common rock."

###

This work was funded by the Australian National University.

The Carnegie Institution for Science is a private, nonprofit organization headquartered in Washington, D.C., with six research departments throughout the U.S. Since its founding in 1902, the Carnegie Institution has been a pioneering force in basic scientific research. Carnegie scientists are leaders in plant biology, developmental biology, astronomy, materials science, global ecology, and Earth and planetary science.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-11/ci-ocb112912.php

kentucky wildcats oakland school shooting nike nfl jerseys katie couric barista university of kentucky ncaa

WebOS raised from the dead again, this time as an Android app [video]

Mitt Romney can take some solace in his devastating loss on Nov. 6: at least he won the voters who really count. That's the thesis anyway of top adviser Stuart Stevens, who penned an op-ed in the Washington Post on Wednesday arguing that by winning wealthier and whiter voters, Romney secured the moral victory over Obama. "On Nov. 6, Mitt Romney carried the majority of every economic group except those with less than $50,000 a year in household income," Stevens wrote. "That means he carried the majority of middle-class voters. ...

Source: http://news.yahoo.com/webos-raised-dead-again-time-android-app-video-035619982.html

fantasy baseball jared sullinger jaleel white levi johnston 2013 srt viper scott walker recall fisker atlantic

Bacteria hijack host cell process, create their own food supply to become infectious

ScienceDaily (Nov. 29, 2012) ? Bacteria that cause the tick-borne disease anaplasmosis in humans create their own food supply by hijacking a process in host cells that normally should help kill the pathogenic bugs, scientists have found.

This bacterium, Anaplasma phagocytophilum (Ap), secretes a protein that can start this process. The protein binds with another protein produced by white blood cells, and that connection creates compartments that siphon host-cell nutrients to feed the bacteria, enabling their growth inside the white blood cells.

The finding defies conventional wisdom about most bacteria, which try to avoid this cellular process. Called autophagy, the process allows a cell to digest parts of itself to produce energy when it is experiencing starvation. But that digestive feature also is enacted by the immune system to help clear away certain intracellular pathogens, including those that cause salmonellosis or shigellosis.

The Ap bacterium, however, launches and then manipulates the autophagy process to its own advantage.

"This study shows how bacteria subvert natural processes," said Yasuko Rikihisa, professor of veterinary biosciences at Ohio State University and lead author of the research. "They are creating their own food supply through a cellular mechanism that hurts other infectious bacteria. And because this process doesn't cause inflammation, they do it very gently, becoming an insider that eventually kills the host cell."

The finding could help identify new targets for drugs to treat this infection, which is a rare but emerging infectious disease that can be lethal for the elderly and people with compromised immune systems. The current first-line treatment is the antibiotic doxycycline.

Also known as human granulocytic anaplasmosis, the disease affects more than 1,000 people per year in the United States, up from just 348 reported cases in 2003, according to the Centers for Disease Control and Prevention. It is transmitted to humans by tick bites primarily from the black-legged tick and the western black-legged tick.

The study appears online this week in the early edition of the Proceedings of the National Academy of Sciences.

The Ap bacterium secretes substances to perform a process resembling mating to infect host cells, primarily the granulocyte class of white blood cells that fight off invading pathogens. Rikihisa's lab previously identified a protein called Ats-1 that is secreted by Ap bacteria during this process.

In this new study, the researchers found that once inside the host cells, Ats-1 binds to another protein called Beclin 1, which is part of a system of molecules involved in the earliest stages of the autophagy process.

The scientists observed that when the two proteins bind, they create little bubbles known as vesicles. Through a series of experiments, the researchers determined that these bubbles were in fact autophagosomes -- bubble-like compartments that are formed as a cell prepares to undergo autophagy.

They were able to confirm this by imaging the vesicles to determine that they had the tell-tale double membrane characteristic of autophagosomes, and by testing for the presence of other compounds that serve as markers of the initiation of the cell-digesting process.

Under normal circumstances, autophagosomes contain the nutrients that are meant to be digested and recycled for other uses -- but in this case, the bacteria take those nutrients to promote their own growth.

That Ats-1 could start this process on its own represents a rare power for a single protein.

"We believe this is the first bacterial protein that has been found to do this," said Rikihisa, also an investigator in Ohio State's Center for Microbial Interface Biology and Comprehensive Cancer Center. "Ats-1 initiates an early stage of the autophagosome, then picks up nutrients from the main body of the host cell and closes the layers."

Most of the action of bacterial growth takes place inside a special compartment that typically doesn't contain many nutrients. But after the Ap bacterial protein starts this process of producing autophagosomes that can encase nutrients, these bubbles fuse with the compartment, creating a steady supply of food at the site of bacterial replication and growth.

The researchers showed this by further imaging the bubbles to determine that an autophagy marker protein could be found both inside and outside of the bacterial growth compartments. They also showed that infected cells did not contain any lysosomes, which are cell parts that perform the actual digestion and degradation of foreign bodies during autophagy.

An experiment in mice deficient in the Beclin 1 protein showed that infection levels were much lower if mice had low levels of this protein -- confirming its role in binding with Ats-1 and producing autophagosomes to promote infection. In cell cultures, the researchers also showed that when Ats-1 was overproduced, bacteria grew 10 times more effectively than they did in cells in which an unrelated protein was overproduced.

All of this activity allows the bacteria to remain hidden from the immune system because the induction of autophagy is considered a normal cell function and it does not produce any inflammation, which would recruit infection-fighters to the scene. Instead, the Ap bacteria set themselves up comfortably inside granulocytes and steadily grow for a few days until they rupture their host cells and generate a strong immune response -- which makes an infected person sick.

In one final experiment, Rikihisa and colleagues blocked autophagosome production in Ap-infected cells using an experimental drug called 3-MA. With that process blocked, bacterial growth declined dramatically.

3-MA is toxic to humans, but its effectiveness in blocking the infectious properties of Ap in cells suggests that its structure could serve as the basis for a safe small-molecule drug, Rikihisa said.

"A similar compound could be a potential treatment to inhibit bacterial growth," she said.

Clarifying the power of Ats-1 in inducing autophagy also suggests that this protein could be an important tool in further studies of this complex cell process that remains poorly understood, she added.

This work was supported by a grant from the National Institutes of Health.

Co-authors include Hua Niu and Qingming Xiong of Ohio State's Department of Veterinary Biosciences; and Akitsugu Yamamoto of the Nagahama Institute of Bioscience and Technology and Mitsuko Hayashi-Nishino of Osaka University, both in Japan.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Ohio State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. H. Niu, Q. Xiong, A. Yamamoto, M. Hayashi-Nishino, Y. Rikihisa. Inaugural Article: Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1218674109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/7okT8j-zmOY/121129111841.htm

justin timberlake michael dyer bachmann bachmann iowa caucus results sickle cell trait sugar bowl

বৃহস্পতিবার, ২৯ নভেম্বর, ২০১২

Boehner, Reid Trade Jabs on Cliff Talks (WSJ)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/267257682?client_source=feed&format=rss

yolo liquidmetal gsa scandal kelis dick clark dies ibogaine jamie moyer

Wave of attacks in Iraq kills at least 43 people

People inspect the scene of explosions in a busy commercial area in Hillah, about 60 miles (95 kilometers) south of Baghdad, Iraq, Thursday, Nov. 29, 2012. A wave of bombings in two Shiite Iraqi cities south of Baghdad has killed and wounded scores of people, police said. (AP Photo/Karim Kadim)

People inspect the scene of explosions in a busy commercial area in Hillah, about 60 miles (95 kilometers) south of Baghdad, Iraq, Thursday, Nov. 29, 2012. A wave of bombings in two Shiite Iraqi cities south of Baghdad has killed and wounded scores of people, police said. (AP Photo/Karim Kadim)

A boy stands next to a destroyed truck at the scene of an explosion in a busy commercial area in Hillah, about 60 miles (95 kilometers) south of Baghdad, Iraq, Thursday, Nov. 29, 2012. A wave of bombings in two Shiite Iraqi cities south of Baghdad has killed and wounded scores of people, police said. (AP Photo/Karim Kadim)

Iraqi women walk through the scene of an explosion in a busy commercial area in Hillah, about 60 miles (95 kilometers) south of Baghdad, Iraq, Thursday, Nov. 29, 2012. A wave of bombings in two Shiite Iraqi cities south of Baghdad has killed and wounded scores of people, police said. (AP Photo/Karim Kadim)

(AP) ? Back-to-back explosions tore through tents housing Shiite pilgrims in southern Iraq Thursday, the deadliest in a wave of bombings that killed at least 43 people nationwide, officials said.

The attacks in Hillah began with a roadside bombing near tents set up for Shiites commemorating the 17th century death of the Prophet Muhammad's grandson, Imam Hussein. That was quickly followed by a car bomb targeting emergency response teams.

The explosions, which occurred in a busy commercial area, killed at least 29 people and wounded as many as 90, a police officer said, making it the deadliest attack in the city this year.

Twisted and charred vehicles were left outside damaged stores as shopkeepers collected their strewn merchandise from the bloodstained pavement. Hillah is 95 kilometers (60 miles) south of Baghdad.

Ali Hussein, 44, was walking near his house when he heard the two thunderous explosions near the commercial area about 200 meters (yards) from his house.

"I rushed to the blast site and I saw burning cars and pieces of flesh everywhere," said Hussein, who owns a grocery store. "There were small blood pools all around the place," he added, blaming the security forces who "should do better in order to protect the innocent people."

Just hours earlier, a parked car exploded near the shrine of Imam Hussein in the Shiite city of Karbala, killing six people and wounding 20, another police officer said.

Karbala, 90 kilometers (55 miles) south of Baghdad, is one of the holiest cities in Shiite Islam and the place where Imam Hussein and his brother, Imam Abbas, are buried. Hundreds of thousands of Shiites flock to their golden-domed shrines every year.

Such religious ceremonies have often been targeted by Sunni insurgents seeking to foment sectarian violence and undermine the Shiite-led government.

A suicide bomber also drove his explosives-laden car into a police checkpoint in the mainly Sunni city of Fallujah, 65 kilometers (40 miles) west of the capital, killing three policemen and wounding 11 others, a police official in the city said.

And in the northern city of Mosul, a parked car bomb went off as a police patrol passed, killing two people and wounded two, police said. Another police patrol was hit by a roadside bomb in the town of Balad Ruz, 70 kilometers (45 miles) northeast of Baghdad, killing one policeman and wounding six others.

In other violence, a roadside bomb killed an Iraqi soldier and wounded five others in Taji, north of Baghdad, and a parked car bomb struck a restaurant in Madain, southeast of the capital, killing a civilian and wounding 12 others, according to police.

Five health officials confirmed the casualty figures. All the officials spoke on condition of anonymity because they weren't authorized to release the information.

The nationwide death toll was the highest since Oct. 27 when 40 people were killed in a string of bombings and other attacks around the country.

Although violence has ebbed since the peak of insurgency several years ago, attacks are still frequent against security forces, government officials and civilians. No one claimed responsibility for Thursday's bombings, but car bombs, shootings and roadside devices are the hallmark of al-Qaida in Iraq.

_____

Associated Press writers Qassim Abdul-Zahra and Sameer N. Yacoub contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-11-29-ML-Iraq/id-3d5e295de10045779481bf27cd4b4b03

amber portwood Phyllis Diller Darla Moore newsweek Tony Scott UFC 151 empire state building

Boeing proposes mediation in talks with engineers union

DEAR ABBY: My wife and I have been married for five years. I recently discovered that she made between 10 and 20 porn videos when she was 19. We got married when she was 27. We have four kids from two previous marriages.I am devastated. When I confronted her about it, she cried harder than I had ever seen. She said she was lost, and it's the biggest regret of her entire life.I understand how hard it can be to tell someone you have done something like this. I haven't led a perfect life either, and I have my own skeletons and things that I would never mention. But still, I can't get over this. ...

Source: http://news.yahoo.com/boeing-proposes-mediation-talks-engineers-union-204641049--finance.html

tornadoes in dallas anchorman 2 kentucky basketball oaksterdam the fray national anthem dallas tornado ncaa basketball

বুধবার, ২৮ নভেম্বর, ২০১২

Researchers identify physiological evidence of 'chemo brain'

Researchers identify physiological evidence of 'chemo brain' [ Back to EurekAlert! ] Public release date: 27-Nov-2012
[ | E-mail | Share Share ]

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

CHICAGO Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Using positron emission tomography combined with computed tomography (PET/CT), researchers were able to detect physiological evidence of chemo brain, a common side effect in patients undergoing chemotherapy for cancer treatment.

"The chemo brain phenomenon is described as 'mental fog' and 'loss of coping skills' by patients who receive chemotherapy," said Rachel A. Lagos, D.O., diagnostic radiology resident at the West Virginia University School of Medicine and West Virginia University Hospitals in Morgantown, W.V. "Because this is such a common patient complaint, healthcare providers have generically referred to its occurrence as 'chemo brain' for more than two decades."

While the complaint may be common, the cause of chemo brain phenomenon has been difficult to pinpoint. Some prior studies using magnetic resonance imaging (MRI) have found small changes in brain volume after chemotherapy, but no definitive link has been found.

Instead of studying chemotherapy's effect on the brain's appearance, Dr. Lagos and colleagues set out to identify its effect on brain function. By using PET/CT, they were able to assess changes to the brain's metabolism after chemotherapy.

"When we looked at the results, we were surprised at how obvious the changes were," Dr. Lagos said. "Chemo brain phenomenon is more than a feeling. It is not depression. It is a change in brain function observable on PET/CT brain imaging."

For the study, Dr. Lagos and colleagues analyzed PET/CT brain imaging results from 128 patients who had undergone chemotherapy for breast cancer. They used special software to help discern differences in brain metabolism before and after chemotherapy. Results were correlated with patient history, neurologic examinations and chemotherapy regimens.

PET/CT results demonstrated statistically significant decreases in regional brain metabolism that were closely associated with symptoms of chemo brain phenomenon.

"The study shows that there are specific areas of the brain that use less energy following chemotherapy," Dr. Lagos said. "These brain areas are the ones known to be responsible for planning and prioritizing."

Dr. Lagos believes that PET/CT could be used to help facilitate clinical diagnosis and allow for earlier intervention.

Research has already shown that patients with chemo brain can benefit from the assistance of nutritionists, exercise therapists, massage therapists and counselors. In one study, cancer patients receiving chemotherapy complained of losing their ability to prepare family meals.

"When the researchers provided these patients with written and planned menus for each meal, the women were able to buy the groceries, prepare the meals and enjoy them with their families," Dr. Lagos said.

Dr. Lagos and her fellow researchers hope that future studies will lead the way to better treatment for patients experiencing this often debilitating condition.

"The next step is to establish a prospective study that begins assessing new patients at the time of cancer diagnosis," she said. "The prospective study has the potential to establish an understanding of the change in brain neurotransmitters during chemotherapy, which may lead to improved treatment or prevention."

###

Coauthors are Jame Abraham, M.D., Gary Marano, M.D., Marc Haut, Ph.D., and Sara Kurian, M.S.

Note: Copies of RSNA 2012 news releases and electronic images will be available online at RSNA.org/press12 beginning Monday, Nov. 26.

RSNA is an association of more than 50,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)

Editor's note: The data in these releases may differ from those in the published abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.

For patient-friendly information on PET/CT, visit RadiologyInfo.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Researchers identify physiological evidence of 'chemo brain' [ Back to EurekAlert! ] Public release date: 27-Nov-2012
[ | E-mail | Share Share ]

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America

CHICAGO Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). Using positron emission tomography combined with computed tomography (PET/CT), researchers were able to detect physiological evidence of chemo brain, a common side effect in patients undergoing chemotherapy for cancer treatment.

"The chemo brain phenomenon is described as 'mental fog' and 'loss of coping skills' by patients who receive chemotherapy," said Rachel A. Lagos, D.O., diagnostic radiology resident at the West Virginia University School of Medicine and West Virginia University Hospitals in Morgantown, W.V. "Because this is such a common patient complaint, healthcare providers have generically referred to its occurrence as 'chemo brain' for more than two decades."

While the complaint may be common, the cause of chemo brain phenomenon has been difficult to pinpoint. Some prior studies using magnetic resonance imaging (MRI) have found small changes in brain volume after chemotherapy, but no definitive link has been found.

Instead of studying chemotherapy's effect on the brain's appearance, Dr. Lagos and colleagues set out to identify its effect on brain function. By using PET/CT, they were able to assess changes to the brain's metabolism after chemotherapy.

"When we looked at the results, we were surprised at how obvious the changes were," Dr. Lagos said. "Chemo brain phenomenon is more than a feeling. It is not depression. It is a change in brain function observable on PET/CT brain imaging."

For the study, Dr. Lagos and colleagues analyzed PET/CT brain imaging results from 128 patients who had undergone chemotherapy for breast cancer. They used special software to help discern differences in brain metabolism before and after chemotherapy. Results were correlated with patient history, neurologic examinations and chemotherapy regimens.

PET/CT results demonstrated statistically significant decreases in regional brain metabolism that were closely associated with symptoms of chemo brain phenomenon.

"The study shows that there are specific areas of the brain that use less energy following chemotherapy," Dr. Lagos said. "These brain areas are the ones known to be responsible for planning and prioritizing."

Dr. Lagos believes that PET/CT could be used to help facilitate clinical diagnosis and allow for earlier intervention.

Research has already shown that patients with chemo brain can benefit from the assistance of nutritionists, exercise therapists, massage therapists and counselors. In one study, cancer patients receiving chemotherapy complained of losing their ability to prepare family meals.

"When the researchers provided these patients with written and planned menus for each meal, the women were able to buy the groceries, prepare the meals and enjoy them with their families," Dr. Lagos said.

Dr. Lagos and her fellow researchers hope that future studies will lead the way to better treatment for patients experiencing this often debilitating condition.

"The next step is to establish a prospective study that begins assessing new patients at the time of cancer diagnosis," she said. "The prospective study has the potential to establish an understanding of the change in brain neurotransmitters during chemotherapy, which may lead to improved treatment or prevention."

###

Coauthors are Jame Abraham, M.D., Gary Marano, M.D., Marc Haut, Ph.D., and Sara Kurian, M.S.

Note: Copies of RSNA 2012 news releases and electronic images will be available online at RSNA.org/press12 beginning Monday, Nov. 26.

RSNA is an association of more than 50,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (RSNA.org)

Editor's note: The data in these releases may differ from those in the published abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.

For patient-friendly information on PET/CT, visit RadiologyInfo.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-11/rson-rip111612.php

zou bisou bisou tim tebow press conference tebow press conference trina rob dyrdek oberon donald driver

Henry Hazlitt (1946) on the risk incentive effects of a ?Use it or Lose ...

During class tomorrow, we will (among other things) explore the risk incentive effects of a ?use it or lose it? tax policy; basically, we?ll discover that such a tax scheme (which basically endows the government with a fractional position in a call option on the firm) discourages risk taking.

Of course, as the famous passage from the book of Ecclesiastes reminds us (specifically, in Chapter 1, verse 9), ?What has been will be again, what has been done will be done again; there is nothing new under the sun?. The following quote is taken from a book published in 1946 by economist Henry Hazlitt, entitled ?Economics in One Lesson?.? The quote provides a nice synopsis of much of what we will discuss in class tomorrow.

?When a corporation loses a hundred cents of every dollar it loses, and is permitted to keep only 60 cents of every dollar it gains, and when it cannot offset its years of losses against its years of gains, or cannot do so adequately, its policies are affected. It does not expand its operations, or it expands only those attended with a minimum of risk. . . .

There is a similar effect when personal incomes are taxed 50, 60, 75 and 90 per cent. People begin to ask themselves why they should work six, eight or ten months of the entire year for the government, and only six, four or two months for themselves and their families. If they lose the whole dollar when they lose, but can keep only a dime of it when they win, they decide that it is foolish to take risks with their capital. In addition, the capital available for risk-taking itself shrinks enormously. It is being taxed away before it can be accumulated. In brief, capital to provide new private jobs is first prevented from coming into existence, and the part that does come into existence is then discouraged from starting new enterprises. The government spenders create the very problem of unemployment that they profess to solve.?

Source: http://risk.garven.com/2012/11/26/henry-hazlitt-1946-on-the-risk-incentive-effects-of-a-use-it-or-lose-it-tax-policy/

justin theroux Bumbo recall USA Basketball taio cruz taio cruz Winter Olympics 2014 powerball numbers

Syria: Twin car bombs in Damascus kill 34 people

DAMASCUS, Syria (AP) ? Twin car bombs ripped through a Damascus suburb on Wednesday, killing at least 34 people and leaving dozens critically wounded, according to state media and hospital officials.

The state news agency, SANA, said two cars packed with explosives detonated early in the morning in the eastern Jaramana suburb, a district that is mostly loyal to President Bashar Assad. The area is populated mostly by Christians and Druse, a minority sect.

A series of car and suicide bombings have struck regime targets in Damascus and elsewhere since last December, raising fears of a rising Islamic militant element among the forces seeking to topple Assad.

Wednesday's car bombs went off in a parking lot located between two commercial buildings. They were detonated within five minutes of one another as groups of laborers and employees were arriving to work.

The blasts shattered windows in nearby buildings, littering the street with glass and debris. Human remains were scattered on the pavement amid pools of blood.

After the first explosion, people rushed to help the injured and then the second bomb went off, said Ismail Zlaiaa, 54, who lives in the neighborhood. "It is an area packed with rush-hour passengers," he said, and added: "God will not forgive the criminal perpetrators."

Ibtissam Nseir, a 45-year-old school teacher, said the bombing struck minutes before she set off for work. She said there were no troops around the district and wondered why the attackers would target it. Nseir blamed opposition fighters for the attack.

"Is this the freedom which they want? Syria is a secure country and it will remain so," she said.

There were conflicting reports about the death toll. Two hospital officials, speaking on condition of anonymity because they were not authorized to talk to the media, said at least 30 bodies were brought to two nearby hospitals. The Britain-based Observatory for Human Rights, which relies on reports from the ground, said 29 people were killed.

The different tolls could not immediately be reconciled. The regime restricts independent media coverage.

Syria's conflict started 20 months ago as an uprising against Assad, whose family has ruled the country for four decades. It quickly morphed into a civil war, with rebels taking up arms to fight back against a bloody crackdown by the government. According to activists, some 40,000 people have been killed since March 2011.

Assad blames the revolt on a conspiracy to destroy Syria, saying the uprising is being driven by foreign "terrorists" ? a term the authorities use for the rebels ? and not Syrians seeking change.

Analysts say most of those fighting Assad's regime are ordinary Syrians and soldiers who have defected, disenchanted with the authoritarian government. But increasingly, foreign fighters and those adhering to an extremist Islamist ideology are turning up on the front lines. The rebels try to play down the Islamists' influence for fear of alienating Western support.

There was no immediate claim of responsibility for Wednesday's bombings.

Rebels fighting to topple Assad are predominantly members of the Sunni Muslim majority. In their push to take Damascus, they have frequently targeted state institutions and troops around the country. They have also often hit districts around the capital with the country's minority communities, perceived to be allied with Assad's Alawite sect, an offshoot Shiite group that dominates the regime.

Downtown Damascus ? the seat of Assad's power ? has also seen scores of car bombs and mortar attacks that have targeted state security institutions and troops, areas with homes of wealthy Syrians, army officers, security officials and other members of the regime.

In May, two suicide car bombers blew themselves up outside a military intelligence building in Damascus, killing at least 55 people. In July, a bomb hit a building in which Cabinet ministers and senior security officials had been meeting, killing the defense minister and his deputy, who is also Assad's brother-in-law. A former defense minister also died in the attack.

And in Hama province, 50 soldiers were killed when a suicide bomber detonated his explosives-laden car near an army checkpoint on Nov. 5. It was one of the deadliest single attacks targeting pro-Assad troops during the 20 months of conflict.

Jaramana district has been frequently targeted in the past weeks, as the rebels push their way into the capital. Ten people were killed and 41 were injured when a car bomb exploded in the district earlier this month.

Elsewhere on Wednesday, fighting between rebels and government troops raged on. Regime war planes struck rebel-held areas in the northern Idlib province and several Damascus suburbs.

The Britain-based Observatory said fighter jets carried out five air-raids against the strategic town of Maaret al-Numan, which the rebels captured last month. The Observatory also reported heavy fighting on the town's southern edge, along a highway linking Damascus with Aleppo in the north.

The rebels' capture of Maaret al-Numan has cut the government's key supply line to Aleppo, Syria's largest city and a commercial center that has seen clashes between rebels and troops since July.

Since the summer, the Syrian military has significantly increased its use of air power in efforts to roll back the rebels' territorial gains, particularly in the northeast, along the border with Turkey.

___

Surk reported from Beirut.

Source: http://news.yahoo.com/syria-twin-car-bombs-damascus-kill-34-people-105701699.html

sparkle sacagawea new hope baptist church associated press foster friess new orleans hornets ghost rider spirit of vengeance

মঙ্গলবার, ২৭ নভেম্বর, ২০১২

Wisconsin: DNR secretary bagged seven-point buck during opener ...

MADISON, Wis. -- Wisconsin Department of Natural Resources Secretary Cathy Stepp has bagged a buck.

DNR officials say Stepp shot a seven-pointer on the opening afternoon of Wisconsin's traditional nine-day gun season Nov. 17. She killed the deer on Wisconsin Conservation Congress delegate Mark Noll's land near Alma in Buffalo County.

Stepp is now two-for-two since becoming DNR secretary. She killed a doe on opening morning last year in Iowa County. That adventure turned bloody for the secretary after she pressed her eye socket too tightly to her scope. The recoil drove the scope into her, gashing her skin.

DNR spokesman Bill Cosh says Stepp survived last week's outing with no injuries.

Source: http://www.twincities.com/wisconsin/ci_22069298/wisconsin-dnr-secretary-bagged-seven-point-buck-during?source=rss

Google News Obama Acceptance Speech 2012 alabama football danielle fishel dow jones Bbc News Selena Gomez

mower awol: Home Improvement Tip From SWF Home Inspections

If there?s a custom tile that you love but your budget won?t allow you to cover the entire bathroom with it, use it as an accent tile and purchase lower-cost field tiles. You?ll save money and still get the look you want.

It is our goal to help Florida homeowners by providing you helpful information to allow you to easily, efficiently and cost effectively enjoy your Florida home.

If there are ever ANY questions about maintaining your home, feel free to call me directly. We are afterall, ?Your property consultants for life?

SWF Home Inspections, Inc

Providing home inspection services to clients throughout SW Florida including Sarasota, Venice, Nokomis, Osprey, Bradenton, North Port, Englewood, Port Charlotte, Punta Gorda, Boca Grande, Arcadia, and surrounding communities.

941-493-4334

info@swfhomeinspections.com

http://www.swfhomeinspections.com

Source: http://www.swfhomeinspections.com/blog/home-improvement-tip-from-swf-home-inspections-saving-costs-on-custom-tile-installation/

yom hashoah yolo liquidmetal gsa scandal kelis dick clark dies ibogaine

Source: http://omucaf.posterous.com/home-improvement-tip-from-swf-home-inspection

cough matt groening brandon phillips summerfest summerfest fidel castro rick santorum

Source: http://mower-awol.blogspot.com/2012/11/home-improvement-tip-from-swf-home.html

911 Google Docs masterchef Dictionary.com Chicago teachers strike yahoo finance september 11 2001

Source: http://implemented-quotation.blogspot.com/2012/11/mower-awol-home-improvement-tip-from.html

monsanto boston weather dr seuss birthday jennifer garner jennifer garner romney michigan derrick williams

Source: http://eloisa-wimsey.blogspot.com/2012/11/mower-awol-home-improvement-tip-from.html

roseanne barr guy fawkes gary johnson gary johnson walking dead where do i vote dixville notch

Source: http://jonesgordon.blogspot.com/2012/11/mower-awol-home-improvement-tip-from.html

rock and roll hall of fame severe weather wichita brian wilson storm chasers david blaine gotye

Hands-on with the Asha 205 and Nokia's Slam quick-sharing feature (video)

Hands-on with the Asha 205 and Nokia's Slam quick-sharing feature (video)

Feature phones don't grace our pages too often, but when Nokia said it had a new Asha to show us, we thought we'd go take a look. We've been following the Asha range since it launched a little more than a year ago, but we were also interested to see Nokia Slam in action, a new Bluetooth quick-sharing feature with Android compatibility. There were no touchscreens in sight as we were introduced to the Asha 205 -- a Series 40 QWERTY handset with a social angle aimed primarily at emerging markets, but also at those who either don't have the cash or the need for a top-of-the-range device. Bearing that in mind, we gave the phone a brief once over, looking at what it does for roughly $62 (excluding taxes, etc.), rather than what it lacks compared with smartphones at higher price points. During the meeting we also glanced over the Nokia 206, which shares many of the same features but isn't part of the Asha family due to its numpad input (see the video and gallery for more details). Head past the break for our thoughts on the Asha 205, and a demo of Nokia Slam in action.

Continue reading Hands-on with the Asha 205 and Nokia's Slam quick-sharing feature (video)

Filed under: , ,

Comments


Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/yi2vVMROJYI/

pekingese tcu football westminster bonnaroo 2012 lineup twisted metal sea lion si swimsuit

Budget battle weighs on shopping season

8 hrs.

The impasse in Congress over the ?fiscal cliff? could be the Grinch that steals Christmas if it isn?t resolved soon.

A record 247 million shoppers visited stores and websites over the four-day Black Friday weekend, up 9 percent from last year, according to the National Retail Federation. They spent an average $423 this year, up 6 percent from last year, for a total of $59 billion.

?I think there's a long way to go,? said retail industry analyst Dana Telsey. ?This season is going to be a battle almost every single day as you keep getting through to those ten days before (December) 25th. I think we go into a lull period now before you get the big sales coming again.?

Even without the uncertainty over a $500 million wave of tax hikes and spending cuts set to hit paychecks Jan. 1, retailers face some major challenges this holiday season.

With unemployment stuck at nearly at 8 percent, millions of households are without paychecks. Still reeling from last month?s Superstorm Sandy, millions of hard-hit households have had to dip into savings to clean up and rebuild. (Based on insurance data from previous storms, as much as half of the estimated $50 billion in property losses may have been uninsured.) Spending on lost household furnishings and damaged homes will divert funds that would otherwise have gone to holiday shopping.

Spending may also fade this holiday season because, continuing a decade-long trend, retailers kicked it off ?even earlier this year. Some consumers have already spent all or part of the money they budgeted for the holidays.

With so much economic uncertainty this year ?retailers started extending their promotional period,? said American Express vice chairman Ed Gilligan. ?Our research says that some people have been holiday shopping since Halloween or even earlier.?

Consumers who haven?t finished ? or even started ? their holiday shopping face continued uncertainty until Congress and the White House reach a budget deal. One of the biggest single hits to spending would come from the expiration of jobless benefits which, unless renewed, would remove $26 billion from consumer spending next year, according to the non-partisan?Congressional Budget Office.

Since the recession hit in 2007, Congress has battled multiple times over the extension of four separate? tiers? of extended benefits. As a result, most beneficiaries are keenly aware of just how vulnerable they are to a last-minute cutoff of those extended tiers.?

All those people facing expiration are going to keep their wallets closed, even if a last-minute deal is reached before year-end.

On Monday, a White House report estimated that letting taxes rise on middle-class families would take a? $200 billion bite out of consumer spending in 2013. That 1.7 percentage point cut in spending would knock 1.4 percentage points off GDP growth, according to the White House's National Economic Council and Council of Economic Advisers.

The retail industry, which has accounted for nine percent of employment growth since the U.S. recession ended in June 2009, would be among the hardest hit, the report said.

The CBO has estimated that, unless modified or postponed, the budget law set to take effect in January will push the U.S. economy back into recession and send the unemployment rate to 9.1 percent ? up from the current 7.9 percent. The budget package would send the nation?s gross domestic product, which grew at a 2 percent annual rate in the third quarter, into reverse, shrinking at a 0.5 percent rate, according to the CBO analysis.

Much of the contraction would come from a sharp slowdown in consumer spending, according to Monday?s analysis by the White House of the impact on middle class consumers.

The report was the latest volley by President Barack Obama in his ongoing political battle to strike a deal with Republicans that would extend tax cuts for families making less than $250,000 a year and raise taxes on people making more.

Shortly after his re-election, Obama called on Congress to extend tax cuts for 98 percent of American families even before wider deal is reached. The White House also wants lawmakers to fix the alternative minimum tax, set up decades ago to remove tax breaks for high-income households. Because it was not indexed for inflation, is has to be fixed every year to avoid snaring in millions of less affluent taxpayers.

Middle class households ? along with all wage earners - will also lose about $68 a week in spending money if the two percent payroll tax holiday is allowed to expire.

Source: http://www.nbcnews.com/business/economywatch/budget-standoff-weighs-holiday-shopping-season-1C7206758

how to hard boil eggs new nfl uniforms easter derbyshire the matrix oceans 11 ferris state hockey

সোমবার, ২৬ নভেম্বর, ২০১২

Evangelicals Becoming More Devout, Catholics Less So

Evangelical Protestants have become more devoted to their religious beliefs over the last three decades, even as Catholics have become less attached to their faith, new research finds.

The denominational differences come even as religious affiliations have decreased overall in America, with the number of people who claim no religious affiliation at all doubling from 7 percent in 1990 to 14 percent in 2000, said study researcher Philip Schwadel, a sociologist at the University of Nebraska, Lincoln.

Nevertheless, Schwadel said, these unaffiliated individuals seem to be dropping out of religious institutions that they were previously ambivalent about. People who feel strongly about their faith are as numerous as ever.

"The proportion of Americans who say they have a very strong religious affiliation over time is very stable," Schwadel told LiveScience.

Strength of faith

Schwadel based his findings on a major questionnaire called the General Social Survey, which has been administered to a cross-section of Americans yearly or every other year since 1974. Among the questions on this survey are several about religion, including one that asks how strongly affiliated people feel about their denomination. [8 Ways Religion Impacts Your Life]

By analyzing about 40,000 responses over the decades, Schwadel was able to track changes in how strongly tied people felt to their religion. He found that the total number of strongly affiliated people stayed basically steady around 37 percent, with a small, short-lived bump to 43 percent in 1984 and 1985.

The people who identified as religious but said they weren't strongly tied to their religion became less common over time, however, dropping from 56 percent in 1990 and 1991 down to 45 percent between 2008 and 2010. This coincided with the uptick in unaffiliated Americans.

"The tremendous growth in being unaffiliated came, I think not very surprisingly, from the relatively uncommitted Americans," Schwadel said.

Changing attitudes

On a denomination-by-denomination level, the picture gets more complex. While the overall number of strongly affiliated people has stayed stable, that's because Evangelical Protestants have become more tied to their churches, while Catholics identify less strongly with their faith.

In the 1970s, there was only about a 5-percentage-point difference in how strongly Catholics and Evangelicals felt about their religion, Schwadel said. Today, it's around 20 percentage points. About 56 percent of Evangelicals currently say they're strongly affiliated with their religion, while only 35 percent of Catholics say the same.

A few things could be driving these trends, Schwadel said, though the survey did not ask people for their reasons behind their religious devotion. Priest sex abuse scandals in the Catholic Church could have shaken people's trust in the institution, so that they still call themselves Catholic but distance themselves from the Church. Likewise, the demographics of Catholicism are changing, Schwadel said. There are more Latino Catholics in America today than in the past, and Latinos may be less likely to strongly identify with the institution of the Church than white Catholics.

On the Protestant side, Evangelicals became more visible during the 1990s, as well as more politicized, Schwadel said. It's possible that broader social influence encouraged more people to identify strongly with the faith.

Both the increase in Protestant devotion and the decrease in Catholic faith happened gradually over time rather than sharply from generation to generation, Schwadel noted in the Autumn 2012 issue of the journal Sociology of Religion. That should offer some reassurance to Catholic leaders disappointed to see their flock less devout.

"When it's that rapid and not really generationally motivated, it may be possible to reverse people's views," Schwadel said.

Follow Stephanie Pappas on Twitter @sipappas or LiveScience @livescience. We're also on Facebook & Google+.

Copyright 2012 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/evangelicals-becoming-more-devout-catholics-less-183200875.html

gina carano at last al green burger king delivery etta james at last john king obama sings al green

First-time buyers shut out of housing recovery

2 hrs.

Current homeowners are finally moving up, and distressed sales are making up less of the overall market?all signs of much-needed improvement in housing.

Current homeowners accounted for 54 percent of October?s non-distressed market, up from 50 percent in June, according to a new survey by Campbell/Inside Mortgage Finance.

This as the share of non-distressed sales surged to 64.7 percent, up from 55.7 percent as recently as February.

Unfortunately, first-time home buyers are seeing just the opposite, largely left out of this surge in sales and prices. Their share of the market, usually up in the 40 percent range historically, fell to 34.7 percent in October, the lowest in the Campbell/IMF survey?s three-year history.

The National Association of Realtors put their share even lower, at 31 percent.

Either way, they are the only group of buyers that have not seen their share of non-distressed home purchases rise over the past five months. The mortgage of choice for these buyers, FHA-insured loans, are increasingly tough to obtain. (Read More: Yes, Housing Starts Surge, but Rentals Are the Drivers)

?Financing of first-time homebuyers with low down payments threatens to become a significant problem in the U.S. housing market,? wrote Thomas Popik, research director for Campbell Surveys. ?Fifty percent of first-time homebuyers use FHA financing, but FHA insurance premiums are increasing and underwriting is becoming more strict. Private mortgage insurance has started to fill the gap, but the long-term status of private mortgage insurance is in question pending the publication of the Qualified Residential Mortgage regulation resulting from Dodd-Frank.? (Read More: Builders Bump Up Thanks to Drop in Existing Home Supply)

Real estate agents answering this latest survey also noted that the recent hike in FHA mortgage insurance premiums is hitting first-time buyers harder because some sellers are refusing to accept offers that include FHA financing. Adding insult to injury, the FHA, after reporting a major shortfall in its insurance reserve funds, announced it would raise premiums yet again, another 10 basis points early next year. (Read More: To Stem Losses, FHA Mortgages Get More Expensive)

Lower priced, distressed properties, like foreclosures and short sales, would seem like the best answer for first time buyers, but hungry, all-cash investors are proving to be too much competition. Investors purchased one fifth of all homes that sold in October, up from 18 percent the previous month, and all-cash buyers (largely investors) made up 29 percent of all sales, according to the Realtors. (Read More: How 'Fiscal Cliff' Could Affect Mortgage Interest Deduction)

This is why, despite increasing household formation, rental occupancies continue to fall and rents to rise. Would-be first time home buyers are either choosing or are forced to rent.

Source: http://www.nbcnews.com/business/housing-recovery-leaving-behind-first-time-buyers-1C7266178

Grandparents Day 2012 army wives 60 minutes go daddy tim tebow Tom Kenny Long Island Medium

রবিবার, ২৫ নভেম্বর, ২০১২

Give the gift of premium Web services

18 hrs.

As you're trying to come up with great gifts for the holidays, software likely isn't the first thing that comes to mind. It can make a great gift for the right person, though, especially when they're not willing to shell out the cash themselves (as so few people are). Here are some of our favorite (and your favorite) premium Web services that not only boost productivity, but dish out a little holiday cheer too.

Note: Most of these are monthly subscriptions, so you can gift them however you like. Giving someone a few months or a year of a service is a great gift that you can tweak for your budget, and leave yourself room for the same gift next year if they really like it.

If a service doesn't offer a gift option, you can always use a prepaid credit card and give it to them for use with the service you're gifting.

SUBSCRIPTIONS?UNDER $5 A MONTH?

A personalized domain name
It?may sound silly for the No.?1 item on our list, but it's the cheapest subscription you can give, costing only $3.99 a year (that's 33 cents a month), and it's something everyone should have. They may not know it, but a personalized domain name can come in extremely handy, and will only get more important as time goes on. They can post their online CV or resume there, redirect it to their Twitter or Facebook page, and further control how the Internet sees you. The quicker you snatch it up before someone else with the same name, the better. We've linked to Namecheap below, since that's your favorite domain registrar, but check out our Hive Five for a few other options.

Crashplan+
If you have a friend who still isn't backing up their data, it's the perfect time to give them the gift of bulletproof backup thanks to Crashplan. Even if they're backing up to an external drive, that isn't good enough???they need something in the cloud so no matter what happens, their backups are always accessible and they don't become another sad story of lost data. Crashplan is our favorite option, being cheap and easy to set up, so get them in the habit now. If you're particularly cheap, RobotTaco notes that you can get a free subscription right now from this page.

LastPass and Xmarks Premium
I
f you know someone with multiple computers, the gift of synchronization can be a wonderful thing. Give them a combined subscription to LastPass and Xmarks for their passwords, bookmarks, history, open tabs, and everything else so they're able to browse easily from any computer.?

Xmarks is convenient, but LastPass is the most important app here, as it gives you the enhanced security everyone should have???make sure they create good passwords and turn on two-factor authentication, while you're at it, so they don't fall prey to the ever-increasing number of hacks happening nowadays.?

The pro versions give you access to the mobile apps for each service, more secure two-factor authentication with a thumb drive or YubiKey, plus an ad-free experience and priority support. You can buy each service separately, but buying them both together gets you a pretty sweet discount.

Pandora One
Everyone loves Pandora, but no one likes ads interrupting their music. Reader jrod3737recommended a subscription to Pandora One as a gift for just about anyone: it not only ditches the ads, but lets you use the Pandora desktop client, customize your experience with skins, and listen to higher quality audio all day long. You can either buy a month-to-month subscription or grab an entire year for a discounted price.

Evernote Premium
Evernote is still your favorite note-taking application, and it's only gotten better lately. If you know someone that isn't using Evernote yet???particularly if they need some extra organization in their life??a subscription to Evernote Premium is a great way to get them started. A premium subscription gets you more space per month, offline notebooks, collaborative notes, better speed, PDF search, priority support, an ad-free experience, and more. It's the perfect way to take someone's organization from good to awesome with one simple download.

SUBSCRIPTIONS UNDER $10 A MONTH

Amazon Prime
Amazon Prime's combination of two-day shipping and sizable library of streaming TV shows and movies makes a fantastic gift for?...?well, anyone who ever uses Amazon. And if they don't use Amazon, they will once they can buy anything with free two-day shipping. Of course, you could always share your two-day shipping benefits with them, but getting them their own subscription lets them stream movies too, which is always nice???especially if they have a home theater PC or streaming set-top box in their living room.

Netflix and Hulu Plus
For the true TV addict, grab them a subscription to Netflix and/or Hulu Plus so they can watch all their favorite movies and TV shows on demand. Netflix is great for movies and TV shows alike, while Hulu Plus is particularly good for watching current seasons of shows as they air. Both subscriptions let you stream to a set-top box, too, and are the perfect companions for ditching an expensive cable subscription. Grab one or both for your friends and help set them free from the shackles of cable TV.

Spotify Premium
If your friend has truly embraced streaming and switched to Spotify for their music-listening needs, they need a premium subscription.?

Not only will it get rid of the ads (which the cheaper "Unlimited" subscription will also do), but it gives them higher-quality audio and lets them listen on their iPhone or Android phone, truly completing the Spotify experience.

?It may not be ready to replace most people's libraries, but if you know someone whose fallen in love with it, you should help them go all-out with a Premium subscription.?

Alternatively, if you don't like Spotify, you can grab them a subscription to one of the other great music services out there, like Grooveshark or Rdio.

FOR THE BIG SPENDERS: SUBSCRIPTIONS $10 A MONTH AND UP

A VPN for privacy and international browsing
A VPN (virtual private network)?may seem like an ultra geeky gift, but it's something not everyone knows they need, and nobody wants to pay for. However, it can be useful for all sorts of people, but especially good for users looking for an extra bit of privacy (like bittorrent users) or, as reader JeshuaSanmentions, those living internationally (who?want to watch Hulu or listen to Spotify when it isn't available in their country). Every user is different, so hit the link below to see some of the VPNs we recommend.

  • Choose a VPN (Subscriptions range from $7.99/month to $38/month)

Extra Dropbox space
Dropbox is one of our all-time favorite Web services, and while you can grab a lot of space for free, sometimes you just need to pony up for a premium subscription. A subscription to expanded space can be great for students, video editors with large files, or people that just want to sync their large musicor photo libraries across computers. Alternatively, you can also grab someone one of the cheaper options, like Google Drive, Skydrive, or Box.

A special thanks goes out to everyone who provided suggestions last week! It made putting together these guides a lot easier, and a better fit for you.

More?from Lifehacker:

Source: http://www.nbcnews.com/technology/technolog/give-gift-premium-web-services-1C7209890

susan g komen kenyon martin kenyon martin big miracle slab city super bowl snacks appleton

Tax write-offs for corporations or LLC's? ? Legal Office

When you form one of those businesses and write off stuff, do you pay less taxes or get more in return for those things you wrote off?

I?m a sole proprietor and thinking of switching to a corporation due to construction work. Own a landscaping business and so we do maintenance and some small construction work. Growing and expanding so looking towards a corporation to protect me from liability.

Source: http://attorney.solve-up.com/attorney/tax-write-offs-for-corporations-or-llcs/

brad and angelina herniated disc sacramento kings luke scott tom benson royals nicole richie

timothywell: How to prevent snoring? | Health and Fitness Tips ...

In everyday life, people who snore are not uncommon, many people think this is a performance sleeping, actually snore may not only lead to suffocation and even the night sudden death, and to influence others sleep.Today to tell you how to prevent snoring.

Methods / steps

1, Enhance physical exercise (preferably mountaineering, running, etc.), enhanced lung function.

2, Experts remind, the snoring if smoking habits you need to quit smoking immediately. Because smoking stimulus will only make the already clogged nasal and respiratory nasal mucosa worse. Drinking heavier snoring, nocturnal breathing disorders and hypoxemia. Especially bedtime Drinking.

3, Obese should actively lose weight.

4, Snoring patients more oxygen content decreased, often accompanied by high blood pressure, heart rhythm disorders, blood viscosity increased burden on the heart, easily lead to the occurrence of cardiovascular and cerebrovascular diseases, so attention should be paid to the monitoring of blood pressure, taking time to drop pressure drugs.

5, Bedtime prohibit taking sedative hypnotics and anti-allergic drugs, so as not to aggravate the conditioned inhibition of the respiratory center.

6, Take a lateral position sleep posture, especially in the right lateral position appropriate to avoid the tongue during sleep, the soft palate, uvula relaxation after the fall, adding to the blockage of the upper airway.

7, Patients after surgery to mainly soft food, do not eat hot food. Avoid strenuous activity.

8, Before going to bed try not to drink tea, coffee.

  • Diet tips for low blood pressure
    1, Better nutrition, eat meat and vegetables , with a reasonable diet, ensure adequate intake of nutrients-round, so that gradually become robust physique from delicate. Eat more such as lotus seeds, ...
  • The supplemental nutrients to removal of athlete?s foot (beriberi)
    The supplemental nutrients to removal of beriberi (athlete's foot ) Vitamin B complex: to promote cell regeneration, prevent beriberi renewable. Vitamin C: is quite important for immune function...
  • Daily skin moisturizing and skin whitening plan in autumn and winter
    Autumn and winter skin begins to dry, is the best time to skin moisturizing and skin whitening. Here to tell us about how whitening and moisturizing , in order to allow water and nutrients penetrate t...
  • How to neck whitening
    Found that neck a lot of black than the facial, how to neck whitening? 1, We must first be thoroughly cleaned before whitening the neck, do not let the old dead skin cells and other impurities rema...
  • Dont drink coffee after alcohol
    People drink, alcohol will be absorbed by the digestive system quickly, and then into the blood circulatory system, thereby affecting the gastrointestinal, heart, liver and kidney, brain and endocrine...
  • The effectiveness and nutritional value of pumpkin
    1, Detoxification: Pumpkin contains vitamins and pectin, pectin has good adsorption, can be bonded and the elimination of bacterial toxins in vivo, and other harmful substances, such as heavy metals...
  • Diet tips for the patients with stomach
    Should pay attention to diet in patients with stomach trouble following 11 principles: 1. Eat less fried food: because this kind of food, not easy to digest, will increase the burden on the digest...
  • Nine collagen cosmetic effect ? what is collagen protein?
    Many skin care products are added in collagen protein and collagen beauty beverages are also very popular, the popular skin care ingredients. Today, we have to analyze the collagen cosmetic effect. ...
  • How to do women dysmenorrhea? ? Tips for women dysmenorrhea.
    How to do for women dysmenorrhea? The first one: Diet 1, A balanced diet, eat too sweet or salty foods, eat more vegetables, fruits, chicken, fish; 2, Drink a glass of hot milk add a spoonful of ...
  • How to improve skin elasticity?
    How do we do to improve skin elasticity? The skin loses its elasticity causes include age, improper rest and stay up all night long, intense sun exposure, a bad habit of exaggerated facial expressions...
Tags: harm of snoring, How to prevent snoring, how to stop snore, no snoring, prevent snoring, stop snore
This entry was posted on Friday, November 23rd, 2012 and is filed under Health Tips. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Source: http://www.hhtip.com/how-to-prevent-snoring/

angelina jolie oscars chardon high school christopher plummer viola davis school shooting in ohio shooting at chardon high school sasha baron cohen

Source: http://timothywell.blogspot.com/2012/11/how-to-prevent-snoring-health-and_25.html

oakland pinnacle airlines kansas vs kentucky joe posnanski michael kidd gilchrist national championship calipari